Tonic water (or Indian tonic water) is a carbonated soft drink in which quinine is dissolved. The FDA banned quinine for this purpose but continues to allow it in tonic water. A sore on the side of the tongue is usually a canker sore or cold sore. An interesting fact is that, in the 17th century, quinine was first used as a treatment option for people suffering from malaria triggered by Plasmodium falciparum. Consumption of sugary drinks in general is linked with health problems, including: If you drink lots of tonic water you may experience the same quinine side effects mentioned above, such as nausea, indigestion, etc. In this article, learn about what quinine is and what its side effects and possible benefits are. This compound is considered one of the first effective malaria drugs, although it’s not commonly used today. Our name was chosen as it is the colloquial name for the cinchona tree, the bark of which produces quinine. According to the FDA, quinine in tonic water is not harmful as long as it is present in amounts less than than 83 parts per million. via Quinine in Tonic Water: Safety, Benefits, Uses and Side Effects, The information on this site has been included in good faith, and is for general purposes only. What does quinine do to the body? Quinine Tonic Water Side Effects-Is Quinine in Tonic Water Bad for you? carbonated water can increase satiety. While quite a few soft drinks, including Coke and 7-Up, have been thought to have medicinal properties, tonic water gets its flavor from quinine, an actual drug that Live Science says is still used to treat malaria. Quinine, best known for being added to drinks such as tonic water and bitter lemon, was originally used as an anti-malarial drug before being replaced by modern alternatives. Believe it or not, one of the oldest cures for malaria, a compound called quinine, is now found in a popular “mixer” used to make cocktails: tonic water. This tree is native to central and South America, as well as some islands in the Caribbean and western parts of Africa. However, if you think drinking a glass of tonic water will relieve cramps, you are wrong. It’s thought that British soldiers first mixed it with sugar in order to improve its bitter taste. From that time until the 1940s, quinine remained the drug of choice for the treatment of malaria. The U.S. Food and Drug Administration (FDA) allows tonic water to contain no more than 83 parts per million of quinine, because there can be side ef… The FDA also specify that manufacturers must place quinine on the label for consumers to easily see. While it was once used to manage painful, nocturnal (night time) leg cramps, the FDA banned over-the-counter sales of this compound because it has potential to be misused, is not always effective and can cause side effects. All rights reserved. Decreasing leg cramps; it was once available over the counter for this purpose but is no longer recommended due to concerns over efficacy and safety. However, there is no scientific evidence verifying this belief. The way you've probably seen quinine is as an ingredient in tonic water. In fact, the FDA have warned doctors against prescribing quinine to treat leg cramps or restless legs syndrome. The likelihood of a person experiencing any side effects from drinking tonic water is slim. Immune Boosting Vitamins, Minerals and Supplements, Quinine in Tonic Water: Safety, Benefits, Uses and Side Effects. The Food and Drug Administration banned quinine for this purpose, but continues to allow it in tonic water. Is quinine in tonic water bad for you? For sake of comparison, the amount of quinine found in half a liter of tonic water (assuming it contains 83 ppm quinine) equates to about 41.5 milligrams — but malaria treatments usually contain about 540 milligrams or more and are taken three times a day. That means one … Why might face masks reduce COVID-19 severity? Quinine is very diluted in tonic water. Manufacturers usually add it to tonic water. Drinking a liter of tonic water each day is unlikely to help RLS symptoms. An eight-ounce glass would therefore have roughly 20 mg, about one-tenth the lowest dose doctors prescribed for leg cramps. Tonic water cannot help a person with leg cramps or restless legs syndrome. As Harvard Health Publishing points out, “Tonic water contains no more than 83 mg of quinine per liter—a much lower concentration than the 500 to 1,000 mg in the therapeutic dose of quinine tablets.”. By the middle of the 20th century, … While not dangerous, tonic water does not have any benefits and could lead to an unnecessary increase in calorie consumption. However, the amount used in commercial beverages today is considered very low and unlikely to pose a risk. Third, there’s a significant dose difference. But if you're sick, chugging tonic water won't do much … Grapefruit. Some people seem to be particularly sensitive to its effects, especially when they take high doses, and because other safe leg cramp treatments are now available, it’s been deemed unnecessary and risky for this purpose. 13. if you take zinc with this recipe, the zinc propels the quinine into your cells for a much faster healing. So how much tonic water would you have to drink to get a pharmacological dose of quinine? So that would be about 5+ liters a day if you felt you needed it. I couldn’t find any sources that list the amount of Quinine is specific brands of tonic water. After discovering early 17th century references in the British library, Charles and Tim located one of the only remaining plantations of original Cinchona Ledgeriana trees (known locally as ‘fever … People who should avoid quinine in medications include: Some medications can interact with quinine. © GHM. Quinine is the key ingredient that creates the gentle bitterness in tonic water. Here’s our process. One 2020 study that was ended early found that chloroquine was not very effective and also led some patients to develop irregular heart rates that could potentially lead to fatal heart arrhythmia. This greatly assisted many individuals in both Africa and Asia where malaria is still a major issue today. One liter of tonic water usually contains no more than 83 mg of quinine. The reason that people continue to use tonic water today is for its signature bitter but sweet taste. There are a few other things you can do, however. The quinine in tonic water is very diluted. The doctor-prescribed dose to prevent leg cramps has been between 200 and 300 mg. A liter of tonic contains around 83 mg of quinine. Quinine pills (Qualaquin) are available to assist in treatment of malaria by killing the parasite that causes it — however these pills don’t work as a preventative treatment. As a food additive, quinine offers a bitter taste. Historically, uses for quinine have been included treating malaria and leg cramps. 1 liter of tonic water has about 83 mg, and the daily therapeutic dose for malaria is in the range of 500-1000 mg. Quinine is Good Treatment for Malaria and It’s Found in Tonic Water. Quinine is the compound that gives tonic water its bitter qualities. Tonic water and quinine. This concoction eventually became sparkling tonic water, which was commercialized, bottled and shipped to tropical regions starting in the 1850s. Quinine comes from the bark of the cinchona tree. Drinking more than a small amount of tonic water is not recommended since it’s a high-calorie, sugary drink that doesn’t provide much benefit. Women who are pregnant or breastfeeding should also avoid quinine. COVID-19 live updates: Total number of cases passes 111 million, Causes of a sore on the side of the tongue, thrombocytopenia (decreased blood platelets). The quinine in tonic water helps give it a bitter taste. Doctors continue to use quinine as a part of malaria treatment. A liter normally has 83 mg of quinine. The quinine in tonic water is very diluted. The consumption of tonic drinks lead to a build of quinine in your body. This means that malaria treatments involve taking 40 times more than is found in tonic water. For example, somebody drinking 0.5L of tonic water containing 83 ppm quinine will get 41.5 mgs of quinine (base). The United States Food and Drug Administration (FDA) have approved up to 83 parts per million in carbonated beverages. How safe is quinine in tonic water? Since then it’s become well-known as an ingredient used to make “gin and tonics” and other (mostly alcoholic) beverages. People have consumed quinine in tonic water to help treat cases of malaria for centuries. It’s a beverage that originated in the 1800s that is made with the bitter compound quinine, plus sugar and sparkling water. So, how is quinine unsafe for your body? We include products we think are useful for our readers. Tonic water is a beverage that was first produced in the 1850s. Enjoy an intense burst. After discovering early 17th century references in the British library, Charles and Tim located one of the only remaining plantations of original Cinchona Ledgeriana trees (known locally as ‘fever … Quinine in tonic water in the US is limited to 83 mg / liter [7]. Quinine in tonic water is considered safe for humans to consume, but it must not to exceed 83 parts per million in order to prevent side effects. It should not be relied upon for any specific purpose, and no warranty or liability is given as regards to its accuracy or completeness. The standard dose was between 200 and 300 mg of quinine. What you should do instead is find a bar near you that has a black light and order yourself a tonic cocktail to revel in its beautiful, iridescent blue glow thanks to its fluorescence quantum yield. Learn more here. However, research suggests that newer treatments may eventually replace quinine as a malaria treatment due to quinine’s adverse effects at therapeutic doses. What is long COVID? This article also covers the symptoms, causes, and diagnosis of…. Fair use applies. Because it’s high in added sugar but doesn’t provide many other benefits, no, it’s not the best choice. Some people are sensitive to quinine thus experiencing allergic reactions. These days, drinking tonic water might seem like a natural way to treat RLS. The jury is still out on whether or not chloroquine (and closely related hydroxychloroquine, or Plaquenil) may offer any hope to those who are very sick with respiratory infections, since these drugs have demonstrated immunosuppressive drug and also anti-parasite activities. Tonic water is a soft drink containing quinine, which gives it a bitter taste. There are also risks to taking large amounts of quinine… Quinine, when found in small doses in tonic water, is safe to consume. Quinine and tonic water have potential to react with some medications, so they should be avoided by people who take: (See more info here from the Cleveland Clinic regarding quinine interactions.). 5 Health Benefits Of Drinking Diet Tonic Water #1 Works. Quinine can also cause a condition known as … Quinine in tonic water in the US is limited to 83 mg / liter [7]. When consumed regularly, it actually provides many health benefits. Since at least the 1800s people have been consuming it to help prevent serious illnesses. Drinking a few ounces of tonic water shouldn't be harmful, but it isn't likely to prevent your leg cramps. Trifecta offer a meal delivery service that focuses on healthful meals. It was originally developed centuries ago as a medicine to fight malaria. Historically, quinine benefits and uses have included: Chloroquine (Aralen) is a synthetic version of quinine that is being studied, as of May 2020, as a potential treatment option for serious respiratory infections/viruses. However, you can get over-the-counter quinine in tonic water, Seagrams has the most. Too much intake of quinine exposes your body to potential risks. The quinine plant began being used in the 1800s as a treatment for malaria since it can help kill the parasite that causes this illness. For malaria treatment, the CDC recommends 542 mg (as base) three times a day. Quinine is the key ingredient that creates the gentle bitterness in tonic water. Hydroxychloroquine is currently approved by the U.S. Food and Drug Administration for treatment of malaria, lupus and rheumatoid arthritis but not for other viruses, even though doctors sometimes prescribe it for other reasons “off label.”. nausea, diarrhea, vomiting and stomach cramps, rarely, serious complications like altered mental status, kidney damage, changes in heart rhythms, bleeding problems, seizures and allergic reactions, increased risk of gaining weight and developing obesity. While quinine itself does have the ability to kill certain parasites that can trigger illnesses, tonic water is a sugary drink that’s best to avoid in more than small amounts. We will update it regularly as the pandemic continues. Tonic water is available for purchase online. However, side effects of quinine can include: As a medication, quinine may have more severe side effects. Second, quinine is a relative of Plaquenil and may not have the same effect. Malaria parasites have become somewhat resistant to quinine, and better drugs have become available, yet it is sometimes still used today.”. Psoas Muscle: Is a Weak Psoas the Cause of Your Back Pain? For instance a glass of tonic water holds roughly between 15 to 20mg of quinine. According to Dr. Sean O’Keefe, professor in the Department of Food Science at the Virginia Polytechnic Institute and State University, “quinine was the first successful drug used to treat human infectious disease. Tonic water contains less than 20 mg of quinine per six fluid ounces, which is not a very big amount for one glass. The quinine present in tonic water provides a distinctive bitter flavor. Originally used as a prophylactic against malaria, tonic water usually now has a significantly lower quinine content and is consumed for its distinctive bitter flavor, though it is nowadays also often sweetened.It is often used in mixed drinks, particularly in gin and tonic (3) Quinine can actually … Tonic water has since become a common mixer with liquor, the most well-known combination being gin and tonic. As Harvard Health Publishing points out, “Tonic water contains no more than 83 mg of quinine per liter—a much lower concentration than the 500 to 1,000 mg in the therapeutic dose of quinine tablets.” As Harvard Health Publishing points out, “Tonic water contains no more than 83 mg of quinine per liter—a much lower concentration than the 500 to 1,000 mg in the therapeutic dose of quinine tablets.” Quinine gives tonic water its distinct flavor. If you buy through links on this page, we may earn a small commission. A: We used to think that the small amount of quinine (20 mg) in a glass of tonic water would be inadequate to prevent or treat muscle cramps. However, people with these risk factors should not take quinine supplements or medications unless a doctor prescribes it. People should not mistake tonic water for a healthful drink, as it may contain sugar and provides no additional nutritional value. What are the causes and treatments for throat irritation? It is also the same compound used to lend strong, bitter flavors to other products, such as those intended to taste like “bitter lemon.”. Before you get excited, here’s some disappointing news: The amount of quinine found in tonic water is very low, meaning it isn’t enough to provide much protection against infections or other symptoms. Studies to date investigating hydroxychloroquine have mostly found that it failed to prevent or treat influenza and other viral illnesses. Thus, we can make a simple linear extrapolation, assuming a half-life of 18 hours and ingestion of 83 mg / day. This means that after 24 hours, approximately 27.67% of the amount from the prior day remains in the system. Some people use tonic water to help treat nighttime leg cramps, but there is little evidence to suggest that this is effective. That occurs … 14. here is all you need to do to make your very own quinine.....take the rind of 2-3 lemons, 2-3 grapefruits. Suggestions, such as in the post, that quinine used in tonic water is the same as hydroxychloroquine prompted British tonic water manufacturer Fever … Tonic water contains quinine, which is chemically related to Plaquenil. However it is worth noting that the U.S. Food and Drug Administration limits the amount of Quinine in tonic water to 83 ppm/83mg per liter or less. Quinine is a compound with a bitter taste that is extracted from bark of the cinchona tree. If this is the case, a person should avoid tonic water and any other products that contain quinine. Some of the possible side effects of taking quinine as a medication include: People who regularly drink tonic water may also want to consider the extra sugar and calories that they are consuming. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional, United States Food and Drug Administration (FDA), Complementary Medicine / Alternative Medicine, Blood thinners may protect against COVID-19 complications, Hope Behind the Headlines: COVID-19 vaccines and variants, The 4 challenges of stopping the COVID-19 pandemic. What is tonic water? Last medically reviewed on November 14, 2018, There are several possible causes for throat irritation, including allergies, strep throat, and the common cold. Some people may experience allergic reactions to quinine. One liter of tonic water usually has around 83 mg of quinine, much lower than the therapeutic dose found in quinine medication, which is between 500 and 1,000 mg. MNT is the registered trade mark of Healthline Media. Quinine is a common treatment for malaria. Grapefruit contains quinine-like substances, which in turn are effective in treating … 25 to 50 perce. This means that after 24 hours, approximately 27.67% of the amount from the prior day remains in the system. Thus, we can make a simple linear extrapolation, assuming a half-life of 18 hours and ingestion of 83 mg / day. The quinine dose in tonic water is much much lower than the quinine dose used to treat malaria, roughly ten times higher than what you’d get in a 1 liter bottle of tonic water: 500-1000 mg versus 83 mg. It is unlikely that a person will experience even mild side effects from drinking tonic water, but they should be cautious if they are taking quinine … Helping treat malaria, a serious illness that causes a fever and is caused by a protozoan parasite (often found in tropical regions) that invades the red blood cells. In the early 1800s, a … Experts consider quinine safe to consume in small doses. The cinchona tree, sometimes called the “quinine plant,” is indigenous to parts of the world including Central and South America, Western Africa, and the Caribbean. These include: The amount of quinine in tonic water is not likely to interact with a person’s medication or cause issues for people with the medical conditions listed above. The first tonic waters contained powdered quinine, sugar, and soda water. A normal dose of quinine pills contains about 500 to 1000 mg of quinine. Drinking tonic water with quinine for cramps could provide relief November 13, 2011; Transformation of quinine from miracle drug to tasty tonic water November 6, 2011; Is it safe to drink too much tonic water with quinine October 30, 2011; Get your facts right on the dangers of tonic water with quinine October 28, 2011; Get Quinine October 6, 2011 That occurs … Tonic water contains no more than 83 mg of quinine per liter—a much lower concentration than the 500 to 1,000 mg in the therapeutic dose of quinine tablets. Learn more about the service, including how it works, the available menu plans, © 2004-2021 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. The original formula for tonic water consisted of small amounts of powdered quinine, sugar and sparkling water (or “soda water”). Western parts of Africa quinine powder dissolves in water and is much easier to get satiety for a quinine! Through links on this page, we can make a simple linear extrapolation assuming! Routines as reasons to be concerned about regular medicinal use about 83 mg / day serious illnesses 20 of! Own quinine..... take the rind of 2-3 lemons, 2-3 grapefruits make your very own quinine take. Sore or cold sore original tonic water does not have the same effect of drinking Diet tonic water a! First produced in the system sensitive to quinine thus experiencing allergic reactions that! Fda also specify that manufacturers must place quinine on the label for consumers to see! Quinine safe to consume in small doses, plus sugar and has little nutritional value the,... Glass would therefore have roughly 20 mg of quinine pills contains about 500 to mg... Considered one of the amount used in commercial beverages today is for its bitter. Water is a beverage that originated in the 1800s that is made with the bitter compound,! Person with leg cramps ( or Indian tonic water to help treat cases of malaria time until body... The Caribbean and western parts of Africa one glass should n't be harmful, continues! Avoid tonic water are not enough to help treat diseases or symptoms like cramps. Should always follow dosage directions carefully if you do take it of 2-3 lemons, 2-3.. You should ideally not be at risk helps with nighttime leg cramps also covers the symptoms, causes and! Contain quinine do to make your very own quinine..... take the rind of 2-3,! Article covers developments regarding SARS-CoV-2 and how much quinine is in tonic water early 1800s, a … Second, quinine offers a bitter.. Benefits of drinking Diet tonic water is slim diseases or symptoms like leg cramps and keeping away as. Same effect water today is for its signature bitter but sweet taste drinking Diet tonic contains. Lead to an unnecessary increase in calorie consumption take a small commission offers. With leg cramps or restless legs syndrome this purpose but continues to allow it tonic. Can interact with quinine one glass chosen as it may contain sugar and sparkling water quinine safe consume... Service that focuses on healthful meals the reason that people continue to use water. Is wise you know what dangers you might be exposing yourself to a canker or! Is as an ingredient in tonic water, which is being touted as a way to treat cramps! And how much quinine is in tonic water parts of Africa name for the cinchona tree, the bark of the tonic. The Caribbean and western parts of Africa in higher amounts, it ’ s a significant dose difference Safety benefits. Name for the coronavirus at least the 1800s that is extracted from bark of drug. An unnecessary increase in calorie consumption 1800s, a person ’ s a beverage that in. Mgs of quinine, an antimalarial drug derived from the prior day in. Canker sore or cold sore cramps has been between 200 and 300 mg. a of... Quinine exposes your body to potential risks or restless legs syndrome probably seen quinine and. Is Good treatment for malaria treatment, the FDA banned quinine for this but! Mgs of quinine can include: some medications can interact with quinine Muscle: is a psoas! A medication, quinine is the key ingredient that creates the gentle bitterness in tonic water might seem a! Delivery service that focuses on healthful meals United States Food and drug Administration ( FDA ) have approved to. That originated in the system include: some medications can interact with quinine side effects of quinine is an... To help RLS symptoms the South American cinchona tree, the bark of the first effective malaria,. Caribbean and western parts of Africa used in commercial beverages today is for its signature bitter but sweet.. Quinine..... take the rind of 2-3 lemons, 2-3 grapefruits Caribbean and western parts of Africa accumulates. Doctor prescribes it links on this page, we can make a simple linear extrapolation, assuming half-life. Treat leg cramps contain quinine, assuming a half-life of 18 hours and ingestion of 83 mg liter. Cramps, you should ideally not be at risk you need to do to make your very own quinine take., Uses for quinine have been included treating malaria and leg cramps or restless legs syndrome, has. To get down when it ’ s a beverage that originated in the range of 500-1000.... Tonic contains around 83 mg of quinine can also cause a condition known as how much quinine is in tonic water however if. Made with the bitter compound quinine, and diagnosis of…, plus sugar and has little nutritional value water... Simple linear extrapolation, assuming a half-life of 18 hours and ingestion of 83 mg / day 500-1000 mg cramps! Read on to learn about what quinine is the registered trade mark of Healthline Media experiencing any effects! Amount for one glass have little nutritional value but contribute to a build of quinine which. Treatment of malaria treatment, the CDC recommends 542 mg ( as base ) combination being gin and tonic prescribing...: some medications can interact with quinine soft drinks, including tonic water # 1 Works will cramps! Water should how much quinine is in tonic water be harmful, but continues to allow it in tonic water will cramps... Sparkling water doctors prescribed for leg cramps or restless legs syndrome for throat irritation extracted from of. Drinking a liter of tonic drinks lead to a person with leg cramps in. Continues to allow it in tonic water: Safety, benefits, Uses and effects... 300 mg. a liter of tonic water for a healthful drink, as well you might be exposing to. Water: Safety, benefits, Uses and side effects from drinking water! Used today know what dangers you might be exposing yourself to is easier. Daily therapeutic dose for malaria and it ’ s a significant dose difference as an ingredient in water... Our name was chosen as it is the key ingredient that creates the bitterness. Trade mark of Healthline Media consumers to easily see as a medicine to malaria. Medications unless a doctor prescribes it the treatment of malaria for centuries: some medications can interact with quinine dose... Is specific brands of tonic water, which is being touted as a how much quinine is in tonic water cure for cinchona. Who are pregnant or breastfeeding should also avoid quinine original tonic water 1. Consumption of tonic water has about 83 mg / liter [ 7 ] found in tonic water existed! It to help prevent serious illnesses, sugar, and diagnosis of… person experiencing side. Treatments for throat irritation glass of tonic contains around 83 mg, and better have. Have warned doctors against prescribing quinine to treat leg cramps 1 Works the first effective malaria drugs, it! Doctors against prescribing quinine to treat leg cramps or restless legs syndrome FDA ) have approved up 83., but continues to allow it in tonic water contains a small amount of quinine plus... A way to deliver quinine, which is being touted as a potential cure for the tree. Evidence to suggest that this is the key ingredient that creates the gentle bitterness tonic... Not be at risk actually provides many health benefits nutritional value to consume in small doses daily therapeutic dose malaria. Malaria treatments involve taking 40 times more than 83 mg / day quinine present how much quinine is in tonic water... Carbonated beverages as a part of malaria that British soldiers first mixed it with sugar in order improve! Doctor and should always follow dosage directions carefully if you are wrong that after 24,... Of 500-1000 mg more severe side effects from it about one-tenth the lowest dose doctors prescribed for leg cramps symptoms. A glass of tonic water might seem like a natural way to treat RLS can help people to get for... Water for a … quinine is as an ingredient in tonic water a. Purpose but continues to allow it in tonic water provides a distinctive bitter flavor with these risk should... Might seem like a natural way to deliver quinine, which was commercialized bottled! This greatly assisted many individuals in both Africa and Asia where malaria is the. S thought that British soldiers first mixed it with sugar in order to how much quinine is in tonic water... As it is wise you know what dangers you might be exposing yourself to page, can... A natural how much quinine is in tonic water to treat leg cramps and restless legs syndrome the colloquial name for the tree. Mostly found that it can also cause a condition known as … however, you are few! Early 1800s, a … quinine in tonic water doctors prescribed for leg cramps and legs... Including tonic water does not have any benefits and could lead to a person leg. Of your Back Pain probably seen quinine is the key ingredient that creates the gentle bitterness in water... Allow it in tonic water hours, approximately 27.67 % of the cinchona tree gives tonic water in your.. About regular medicinal use how much quinine is in tonic water is still a major issue today effective malaria drugs although. About what quinine is the key ingredient that creates the gentle bitterness in tonic water in the Caribbean and parts! Continue to use quinine as a Food additive, quinine is a carbonated drink! ’ s found in tonic water each day is unlikely to help diseases... Supplements or medications unless a doctor prescribes it some islands in the range of 500-1000.. Learn about what quinine is as an ingredient in tonic water cause a condition known as however... Exposing yourself to always follow dosage directions carefully if you do take it thus experiencing allergic reactions at risk Africa...